Research Applications
Cognitive decline and cerebral cortex function normalization. Stroke recovery. Age-related neurodegeneration.
Mechanism of Action
Cortagen penetrates the nuclear membrane and interacts with DNA regulatory regions in cortical neurons, modulating transcription of genes involved in neurotransmitter metabolism, synaptic protein synthesis, and anti-apoptotic pathways.
Biological Pathways
Cognitive function, Brain health
Dosage Information
Calculation Results
Syringe Fill Level (100u syringe)
Protocols
No protocols featuring this peptide yet.
Browse All ProtocolsSide Effects & Precautions
Minimal reported
Research Use Only. This information is for educational and research purposes only. Not intended for medical advice or self-medication.
Research Studies
Peptide Bioregulators of the CNS
Khavinson VK, Malinin VV.
Frequently Asked Questions
Cortagen is a synthetic tetrapeptide (Ala-Glu-Asp-Pro) bioregulator targeting cerebral cortex function, developed by the Khavinson group. It is designed to normalize neuronal function in the cerebral cortex by modulating gene expression related to neurotransmitter synthesis, synaptic plasticity, and neuroprotection. Preclinical studies show improved cognitive function, enhanced memory, and neuroprotective effects in models of cerebral ischemia and age-related cognitive decline.
Cortagen penetrates the nuclear membrane and interacts with DNA regulatory regions in cortical neurons, modulating transcription of genes involved in neurotransmitter metabolism, synaptic protein synthesis, and anti-apoptotic pathways.
Cognitive decline and cerebral cortex function normalization. Stroke recovery. Age-related neurodegeneration.
Cognitive function, Brain health
Minimal reported
