Abstract
Essential information on maintaining peptide stability through proper storage conditions, reconstitution techniques, and handling procedures. Covers lyophilized and reconstituted peptide storage.
Proper storage and handling of peptides is crucial for maintaining their biological activity and research integrity. This guide provides evidence-based recommendations:
Lyophilized (Powder) Storage:
- Store at -20°C to -80°C
- Keep in original sealed vial with desiccant
- Stability: typically 2-3 years when properly stored
- Avoid repeated freeze-thaw cycles
Reconstituted Solution Storage:
- Refrigerate at 2-8°C for short-term (up to 2 weeks)
- Freeze at -20°C for longer storage (up to 3 months)
- Use bacteriostatic water for extended stability
- Aliquot into smaller portions to minimize freeze-thaw
Handling Best Practices:
- Always use sterile techniques
- Protect from light exposure
- Avoid vigorous shaking; gently swirl
- Allow to reach room temperature before reconstitution
- Record reconstitution date and concentration
Following these guidelines ensures optimal peptide stability and reproducible research results.
