Abstract
A detailed comparison of various growth hormone secretagogues including GHRP-6, GHRP-2, Ipamorelin, and CJC-1295. Analyzes efficacy, side effect profiles, and optimal usage protocols.
Growth hormone secretagogues (GHS) represent a class of peptides that stimulate endogenous growth hormone release. This analysis compares major compounds:
GHRP-6:
- Strong GH release, moderate ghrelin activity
- May increase appetite significantly
- Effective for muscle growth and recovery
GHRP-2:
- Potent GH release, less ghrelin activity than GHRP-6
- Minimal appetite increase
- Good balance of efficacy and tolerability
Ipamorelin:
- Selective GH release without affecting cortisol/prolactin
- Minimal side effects
- Ideal for long-term use
CJC-1295:
- Long half-life (allows less frequent dosing)
- Sustained GH elevation
- Often combined with other GHS for synergistic effects
Clinical applications include muscle wasting, age-related GH decline, and recovery from injury. Dosing protocols vary based on individual goals and peptide selection.

